Excited to finally announce our new funding of the NCI U01 grant CA25048 entitled: “Image-based models of tumor-immune dynamics in glioblastoma”<\/p>\n
Contact MPI: Kristin Swanson
\nMPI: Leland Hu, MD (Radiology, Mayo Clinic)
\nMPI: Peter Canoll, MD, PhD (Director of Neuropathology, Columbia Univ)<\/p>\n
This $3.8M award will support our ability to resolve the dynamics of the human immune system within the glioblastoma microenvironment during the course of a patients’ care.<\/p>\n
Abstract: Our inability to explain why some patients do not respond to immunotherapy, combined with our inability to
\npredict the responders, poses a serious challenge to advancing cancer care and research. Currently, biopsies
\nserve as the most informative way to assess the immunological activity within a cancerous area, but we are
\nspatially and temporally limited in the number of biopsies we can obtain from patients, especially in cases of
\nbrain cancer. We propose here a novel strategy merging artificial intelligence and mechanistic modeling to
\nreveal the spatial and temporal tumor-immune landscape within patients by connecting a unique resource of
\nimage-localized biopsies and clinical imaging for cohorts treated with standard and immunotherapies.<\/p>\n","protected":false},"excerpt":{"rendered":"
Excited to finally announce our new funding of the NCI U01 grant CA25048 entitled: “Image-based models of tumor-immune dynamics in glioblastoma” Contact MPI: Kristin Swanson MPI: Leland Hu, MD (Radiology, Mayo Clinic) MPI: Peter Canoll, MD, PhD (Director of Neuropathology, Columbia Univ) This $3.8M award will support our ability to resolve the dynamics of the … <\/p>\n