Research Scientist
M.S. Applied Mathematics
David joined the lab in the summer of 2010. He is currently working on modeling radiation therapy to account for patient specific tumor kinetics and optimization algorithms as well as helping out with all things software.
ARTICLES
C.H. Holdsworth, D. Corwin, R.D. Stewart, R. Rockne, A.D. Trister, K.R. Swanson, M. Phillips. Adaptive IMRT using a multiobjective evolutionary algorithm integrated with a diffusion-invasion model of glioblastoma. Phys Med Biol. 2012 Dec 21;57(24):8271-83
A. L. Baldock, R. C. Rockne, A. D. Boone, M. L. Neal, A. Hawkins-Daarud, D. M. Corwin, C. A. Bridge, L. A. Guyman, A. D. Trister, M. M. Mrugala, J. K. Rockhill and K. R. Swanson. From Patient-Specific Mathematical Neuro-Oncology to Precision Medicine. Front. Oncol., 02 April 2013
Baldock A L, Ahn S, Rockne R, Neal M, Corwin D, Malone H, Ebaina V, Sonabend A, Mrugala M, Rockhill J K, Rostomily R, Silbergeld D L, Lai A, Cloughesy T, McKhann G, Bruce J, Canoll P, Swanson K R. Patient-specific metrics of invasiveness reveal significant prognostic benefit of extensive resection in a subset of less diffuse malignant gliomas. Submitted
D. Corwin, C.H. Holdsworth, R. Rockne, A.D. Trister, M. Mrugala, J. Rockhill, R.D. Stewart, M. Phillips, K.R. Swanson. Toward patient-specific, biologically optimized radiation therapy plans for the treatment of glioblastoma. Submitted
ABSTRACTS
D. Corwin, C.H. Holdsworth, R. Rockne, R.D. Stewart, M. Phillips, K.R. Swanson. Variability in Glioblastoma Behavior and Optimal Radiation Therapy Dose Distributions. The 7th International Congress of Industrial and Applied Mathematics (ICIAM), Vancouver, British Columbia, Canada, 2011
C. H. Holdsworth, D. Corwin, R. D. Stewart, R. Rockne, K. R. Swanson, M. Phillips. Biologically Optimized 4D Dose Distributions for the Treatment of Incurable Glioblastoma. Annual Meeting of American Association of Physicists in Medicine (AAPM). Vancouver, British Columbia, Canada, 2011
K. R. Swanson, R. Rockne, C. H. Holdsworth, D. Corwin, R. D. Stewart, M. H. Phillips. Improving Treatment Response by Designing Patient-Specific Optimized Radiation Therapy Dose Distributions Informed by Glioma Proliferation and Invasion Kinetics: A Case Study. Annual Meeting of the Radiological Society of North America (RSNA), Chicago, IL, November 2011
D. Corwin, R. Rockne, R.D. Stewart, M. Phillips, K.R. Swanson. Validation of a Patient Specific Model of Glioma Growth and Radiation Response Using Virtual Clinical Trials. University of Washington Pathology Department Annual Retreat, Seattle, WA, September 2011
D. Corwin, C. Holdsworth, R.D. Stewart, R. Rockne, K. R. Swanson. Patient-Specific Mathematical Radiation Oncology: 4D Optimized Dose Distributions Informed by Glioma Kinetics of Proliferation and Invasion. Annual Meeting of the Society for Neuro-Oncology (SNO), Orange County, CA, November 2011
D. Corwin, C. Holdsworth, R.D. Stewart, M. Philips, R. Rockne, K. R. Swanson. Using patient-specific IMRT optimization and a mathematical model of glioma to improve tumor control and reduce normal tissue complications. Annual Meeting of the Radiation Research Society (RRS), San Juan, Puerto Rico, September 2012
D. Corwin, C. Holdsworth, R. D. Stewart, R. Rockne, K. R. Swanson. Virtual clinical trials: Implications for spatially optimizing radiotherapy using a patient-specific model of glioma. Annual Meeting of the Society for Neuro-Oncology (SNO), Washington, DC, November 2012
D. Corwin, C. Holdsworth, R. D. Stewart, R. Rockne, K. R. Swanson. Reducing dose to normal tissue while improving tumor control in human glioblastomas using a patient-specific mathematical and radiotherapy optimization algorithm. Annual Meeting of the Society for Neuro-Oncology (SNO), Washington, DC, November 2012
Baldock, S. Ahn, R. Rockne, M. Neal, D. Corwin, K. Clark-Swanson, G. Sterin, A. D. Trister, H. Malone, V. Ebiana, A. M. Sonabend, M. Mrugala, J. K. Rockhill, D. L. Silbergeld, A. Lai, T. Cloughesy, G. M. McKhann, J. N. Bruce, R. Rostomily, P. Canoll, K. R. Swanson. Patient-specific invasiveness metric predicts benefit of resection in human gliomas. Annual Meeting of the Society for Neuro-Oncology (SNO), Washington, DC, November 2012
Hawkins-Daarud, A. Baldock, C. Bridge, D. Corwin, J. Rockhill, M. Mrugala, R. Rockne, K. R. Swanson. Revealing the diffuse extent of gliomas to enable surgical and radiotherapy treatment design:Insights from a Patient-Specific Mathematical Model and an Untreated Glioblastoma. Annual Meeting of the Society for Neuro-Oncology (SNO), Washington, DC, November 2012
D. Corwin, C. Holdsworth, R. D. Stewart, R. Rockne, K. R. Swanson. A patient-specific, mathematical approach to optimizing IMRT dose plans for glioblastoma. Feinberg School of Medicine Research Day, Chicago, IL, April 2013
D. Corwin, C. Holdsworth, R. Rockne, R. D. Stewart, M. Phillips, K. R. Swanson. Optimizing radiotherapy for Glioblastoma using a patient-specific mathematical model. Annual meeting of the American Association of Physicists in Medicine (AAPM), Indianapolis, IN, August 2013
TALKS
Glioblastoma Behavior and Optimal Radiation Therapy Dose Distributions. University of Washington Applied Mathematics Master’s Symposium. Seattle, WA 2011.
Using a patient-specific mathematical model and an adaptive, evolutionary optimization algorithm to improve radiotherapy treatment planning for human glioblastoma. Mathways Into Cancer II, Carmona, Spain 2013
Modeling patient-specific treatment and response using a proliferation-invasion model and an evolutionary algorithm for radiation treatment planning. Annual Meeting for the Society of Mathematical Biology (SMB), Tempe, AZ 2013